APPROACHES TO THE SUPPLEMENATION OF SELENIUM IN THE PREVENTION OF KESHAN DISEASE
- VernacularTitle:补充硒预防克山病的途径和方法的研究
- Author:
Guangqi YANG
- Publication Type:Journal Article
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Four different methods are suggested for the practical supplementation of selenium to the residents in Keshan Disease areas. They are: distribution of selenite tablets, enrichment of table salt with sodium selenite, use of foliar sprays on grain crops and selection of relatively selenium-rich foods in affected areas.Selenium contents of corn and rice could be raised to a level of about 0.07 and 0.05 pprn respectively by application of foliar sprays. A vailability of the increased selenium is similar to that occurred naturally in corn, as demonstrated by animal experiment. Furthermore, by this method the bio-availability of selenium is better than the other methods of administration.Observation on residents who were treated with selenite table salt for three years and three months revealed that the salt enriched with 10 ppm of sodium selenite is enough to maintain the residents' hair selenium concentration to a level above 0.2 ppm, if an average of 15 g of the salt could be taken from meals daily by an adult. Either by calculation based upon 10 ppm of sodium selenite concentration suggested or by dietary survey, a daily selenium intake of around 60 ?g is required to maintain such a hair selenium level.Since about a half-year's administration is required in order to raise the hair selenium level above 0.2 ppm, an extraoral selenite tablet supplementation seems needed during the early stage of Se table salt treatment.Availability of selenium in selenite iodized table salt is not altered either after one-year storage or after manufacture for fermented soybean curd or salted vegetables. No harmful substance was detected during manufacture of dishes as evidenced by animal experiment.Fresh water products such as shrimps, eels, small fishes and loaches, as well as various species of mushrooms were found to be selenium-rich foods in Keshan Disease area. Their selenium contents ranged from 0.3 to 1.0 ppm.The authors are of the opinion that one may select any method introduced above and at the same time urge the people to take more selenium-rich foods in their diets, thus residents in Keshan Disease areas would obtain enough selenium to prevent them from being seleniumdeficient.
