THE USE OF IODIZED OIL FOR THE PREVENTION OF ENDEMIC GOITER IN RATS
- VernacularTitle:碘化油在防治大鼠试验地方性甲状腺腫上的效用
- Author:
Changying CHANG
- Publication Type:Journal Article
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
An experimental endemic goiter has been produced in rats with a diet which is adequate in every respect except iodine. The goiter can be prevented by giving each rat KI corresponding to 2-3 ?g of iodine daily to the deficient diet.Feeding experiments to assure the availability of idoine in an iodized soybean oil for the prevention of endemic goiter have been performed. The iodized oil, containing 34％ I, was prepared by an improved method. It has been found that icdine contained in the iodized oil has practically the same preventing effect as KI on endemic goiter in rats.Experiments have also been made to ascertain whether iodine in the iodized oil will be lost in the ordinary cooking proccesses. The iodized soybean oil was diluted ten thousand times with sesame oil, and heated up to 200℃ for 15 minutes with frequent stirring. The heated oil was used to take the place of iodized soybean oil in the above feeding experiments. Results show that heating does not cause any appreciable loss of the goiter-preventing effect.From the experimental results given above, it is suggested that iodized oil mixed with edible oils in the proportion of one to 60-300 thousand can be advantageously used for the prevention of endemic goiter in man.
