Regulation on phenotypic and functional maturation of dendritic cell by met-enkephalin
- VernacularTitle:蛋氨酸脑啡肽对树突状细胞表型及功能的影响
- Author:
Ning WANG
;
Yanjie XIA
;
Fengping SHAN
- Publication Type:Journal Article
- Keywords:
Methionine-enkephalin;
Dendritic cells;
Phenotype;
Functional maturation;
Effect
- From:
Chinese Journal of Immunology
2000;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the mechanism of immunomodulatory effects of methionine-enkephalin(MENK)on dendritic cells(DC).Methods:We used scanning electronic microscope for DC morpholopy,assay for acid phosphatas activity,flow cytometry(FCM) and ELISA to study the effects of DC by MENK.Results:MENK(10-12mol/L) could increase the expression of MHC classⅡ,CD86 and CD40 molecules on DC surface(P