Advances of Oct4 gene research
- VernacularTitle:Oct4基因的研究进展
- Author:
Pengsheng ZHENG
;
Haozhe CAO
- Publication Type:Journal Article
- Keywords:
Oct4;
POU5F1;
regulation passageway;
tumor
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Oct4 gene,a member of POU transcription factor family,is expressed in embryonic stem(ES) cells and embryonic carcinoma(EC) cells,but not in cells of differentiated tissues.It plays a critical role in maintaining pluripotent and self-renewing state of embryonic stem cells.The molecular structure,function,regulation passageway and the relationship with tumors of Oct4 gene have been briefly reviewed.
