Role of klotho protein in the pathogenesis of hypertension
- VernacularTitle:Klotho蛋白在高血压发病中的作用
- Author:
Yajun HE
;
Xianming SU
;
Xinyang WANG
- Publication Type:Journal Article
- Keywords:
klotho protein;
nitric oxide;
aging;
hypertension
- From:Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of klotho protein in the pathogenesis of hypertension. Methods We collected blood samples of 104 patients with hypertension and 61 people without hypertension admitted to our hospital between March and June 2009. Klotho protein and nitric oxide (NO) in blood serum were detected by ELISA and nitro-reductase methods. Results Klotho protein absorbance and NO were lower in hypertension group than in non-hypertension group (P
