Achievements of Basic Research in Small-for-Size Liver Transplantation
- VernacularTitle:小体积肝移植的基础研究进展
- Author:
Liang LIANG
;
Tingbo LIANG
- Publication Type:Journal Article
- Keywords:
Small-for-size liver transplantation;
Portal hypertension;
Hepatic sinusoidal microcirculation;
Endothelin-1
- From:
Chinese Journal of Bases and Clinics in General Surgery
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To introduce the mechanisms of graft injuries after small-for-size liver transplantation and protective measures.Methods Recently relevant literatures were reviewed and summarized.Results Portal hypertension after small-for-size liver transplantation induces mechanical injuries as well as hepatic sinusoidal microcirculation disturbance and cytokines release,which worsened the injuries.Decrease portal pressure by surgery or drug could improve grafts function.Conclusion Comprehending the mechanisms of graft injuries will contribute a lot for the living donor liver transplantation.