Influence of defatting procedure on immunogenicity of cancellous bone allograft
- VernacularTitle:脱脂程序对异体松质骨免疫原性影响的实验研究
- Author:
Jialiang ZHU
;
Shuxun HOU
;
Hongbin ZHONG
- Publication Type:Journal Article
- Keywords:
allograft,cancellous bone,transplantation,defatting,immunogenicity
- From:
Orthopedic Journal of China
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
D and the differences between groups were statistically significant(P0.05).Proliferation index increased in the early phase and reached the peak at the 4th post-operative week.Level of proliferation index in four groups was gradiently decreased from group A to group D.At the 4th post-operative week,differences of proliferation index were statistically significant between groups(P0.05).The changing trend of ratio of CD4+/CD8+ was similar to that of proliferation index.Histological observations showed inflammatory cells infiltrated in early phase gradiently decreased from group A to group D.At the 4th post-operative week,histological observations showed neovascularization in group D.At the 8 weeks post-operatively,more new bone formation was observed in group D. The correlation analysis showed significant positive correlation between proliferation index,CD4+/CD8+ ratio at the 4th post-operative week and the content of total lipid (P
