Three Dimensional MRI of Male Schizophrenia Patients and the Relationship Between Their Symptoms and Brain Structure
- VernacularTitle:阴性症状为主的精神分裂症男性患者认知功能及灰质密度改变
- Author:
Weijun SITU
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Voxel-based morphometry(VBM);
Gray matter;
Cognitive function
- From:Chinese Journal of Clinical Psychology
1993;0(02):-
- CountryChina
- Language:Chinese
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Abstract:
Objective:To explore the pathological mechanism of brain structure in schizophrenia male patients with predominant negative symptoms by Voxel-based Morphometry(VBM) and Wiconsin Card Sorting test(WCST).Methods:Schizophrenia patients were assessed by the Scale for Assessment of Positive Symptoms(SAPS),the Scale for Assessment of Negative Symptoms(SANS).Finally,fifteen male schizophrenia with predominant negative symptoms and fifteen matched healthy controls participated in the study and finished the Wisconsin Card Sorting Test(WCST) and 3D MRI scans.Results:The total trails,the number of response errors and perseverant response errors of WCST in the patient group were significantly higher than those in the control group(P
