Expression of HIF-1? and VEGF in synovium of knee joint in adjuvant-induce-arthritis rat
- VernacularTitle:HIF-1?和VEGF在佐剂性关节炎大鼠膝关节滑膜的表达
- Author:
Yudong XU
;
Xinmei SONG
;
Hongtao JIN
;
Shaojun ZHANG
- Publication Type:Journal Article
- Keywords:
HIF-1?;
VEGF;
Adjuvant-induce-arthritis rat;
Synovium
- From:
Chinese Journal of Immunology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of HIF-1? and VEGF and the correlation with pathological score of synovium in adjuvant-induce-arthritis rat knee joint.Methods:Models of adjuvant arthritis(AA) in rats were made successfully,the arthral pathological score was calculated,production of HIF-1? and VEGF protein was assayed by histoimmunochemical staining at different stage after CFA inoculation.Results:The HIF-1? and VEGF concentration in experimental group were higher than that in control group,and there was significant difference(P
