Preparation of metallic wear particles around joint prosthesis by vacuum ball mill in vitro
- VernacularTitle:真空球磨法体外制备人工关节金属磨损颗粒
- Author:
Ming CHENG
;
Min DAI
;
Hucheng LIU
- Publication Type:Journal Article
- Keywords:
joint prosthesis,biocompatible material,wear particle,vacuum ball mill
- From:
Orthopedic Journal of China
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate a method of in vitro preparation and separation for metallic wear particles around joint prosthesis,and evaluate its feasibility in medical experiments of prosthetic loosening.[Method]Metallic wear particles were made around joint prosthesis by vacuum ball mill in vitro.Particle size,size distribution,chemical composition and shape were characterized by element trace analysis,laser countersizer,scanning electron microscopy.Metal particles were co-cultured with RAW264.7 cells,and its cytotoxicity was detected.[Result]Metal particles made by vacuum ball mill in vitro was similar to particles extracted in vivo(
