Expression and pathological significance of CD-147 protein in osteosarcoma
- VernacularTitle:CD-147在骨肉瘤中的表达及其与临床病理指标的相关性实验研究
- Author:
Qiang LU
;
Gang LV
;
Yanfeng WANG
- Publication Type:Journal Article
- Keywords:
CD-147,osteosarcoma,giant cell tumor of bone,immunohistochemistry
- From:
Orthopedic Journal of China
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the expressions of CD-147 in osteosarcoma samples and to research clinically pathological significance. [Methods]The expressions of CD-147 was detected by immunohistochemistry SABC method in 55 cases of osteosarcoma samples.[Results]The moderate/strong expression of CD-147 was 54.5% compared with giant cell tumor of bone.And the high expressions of CD-147 was in close correlation with diagnosis and prognosis in osteosarcoma.[Conclusion]CD-147 were overexpressed in osteosarcoma,which can be relevant to the malignant progression of osteosarcoma.
