Role of estrogen in the development of osteoarthritis and osteoporosis
- VernacularTitle:雌激素在骨关节炎及骨质疏松中的作用研究
- Author:
Haidong LI
;
Leisheng JIANG
;
Liyang DAI
- Publication Type:Journal Article
- Keywords:
estrogen;
osteoarthritis;
osteoporosis
- From:
Orthopedic Journal of China
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
In this paper the latest studies on the role of estrogen for the development of osteoarthritis and osteoporosis in postmenopausal women are reviewed.Estrogen can influence the pathophysiology of osteoarthritis through its interactions with the estrogen receptors,type Ⅱ collagen,cytokines and reactive oxygen species.While in the process of osteoporosis,estrogen can not only influence the estrogen receptors,cytokmes,reactive oxygen species,but also affect the sex hormone binding globulin and estrogen receptor-related receptor.
