Combination of calcium phosphate cement and micromorselized bone for repairing rabbit radius defect
- VernacularTitle:磷酸钙骨水泥复合微小颗粒骨修复兔桡骨缺损
- Author:
Jianping LIANG
;
Xingyan LIU
;
Baofeng GE
- Publication Type:Journal Article
- Keywords:
calcium phosphate cement;
micromorselized bone;
bone defect;
rabbit
- From:
Orthopedic Journal of China
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To confirm the effect of combination of calcium phosphate cement and small amounts of autoallergic micromorselized bone for reparing bone defect and provide the basis for clinical use.[Method]The animal models of bilateral radius defect were created by surgery on Japan white big ear rabbits.The combination with a ratio of 3 to 1 in one lateral leg was implanted in experimental group,and calcium phosphate cement was used in the control group.The X-rays,bone density,and maximum torsional moment were carried out at different time points,and osteogenesis and degradation of the materials in the two groups were analyzed.[Result]Enhancement of osteogenesis was found in the experimental group,and the materials were enclosed significantly by bony callus at the 8~(th) week,the defects were repaired and the materials were degraded completely at the 16~(th) week.The bone mineral content in the experimental group was higher than that in the control group(P