Inhibition of human cancer cell lines by recombinant trichobakin
- Author:
Nguyen Thuy Ha
- Publication Type:Journal Article
- Keywords:
cancer, trichobakin
- MeSH:
Neoplasms;
Therapeutics;
drugs
- From:Journal of Vietnamese Medicine
2003;284(5):26-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Recombinant trichobakin (TBK) has been subjected to study its capacity in inhibiting the growth of three lines of human cancer cell - epidermoid carcinoma of the mouth (KB), rabdomyo sarcoma (RD-26) and myelo sarcoma (2/0-Ag-14), it has been shown that TBK has inhibited the cancer cells. Myeloma sarcoma cells were inhibited by TBK at the lowest dose (ID50 2.55 microgram/ml). For RD-26 and KB cell lines, ID50 = 7.27microgram and 10.5 microgram/ml respectively. After 2 year preservation, protein recombinant contains almost the same inhibition activity from its original one
