Clinical results of medical ozone combined with sodium hyaluronate for knee osteoarthritis
- VernacularTitle:臭氧联合玻璃酸钠治疗膝骨性关节炎的疗效观察
- Author:
Jiafu ZHANG
;
Xiangqing ZHAN
;
Hongwei HU
- Publication Type:Journal Article
- Keywords:
osteoarthritis;
knee;
ozone;
sodium hyaluronate;
treatment
- From:
Orthopedic Journal of China
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To observe the clinical effects of medical ozone(O3)combined with sodium hyaluronate(SH)in treatment of knee osteoarthritis.[Methods]One hundred and twenty patients with knee osteoarthritis were randomly divided into three groups:A,B and C(40 in each group).The patients in group A were treated with intra-articular injection of 15 ml(35 ug/ml)medical ozone in the first week,25 mg sodium hyaluronate in the second week and repeated 15 ml(35 ug/ml)medical ozone in the third week.The patients in group B were treated with intra-articular injection of 15 ml medical ozone once a week for 3 weeks.The patients in group C were treated with intra-articular injection of 25 mg sodium hyaluronate once a week for 5 weeks.VAS score and clinical results of the three groups were recorded and compared preoperatively and at 1,2 and 3 months postoperatively.[Results]The VAS score of three groups were signifcantely reduced after treatment(P