Research Progress on Genotoxity of Polycyclic Aromatic Hydrocarbons
- VernacularTitle:多环芳烃遗传毒性研究进展
- Author:
Xinxin WANG
;
Yinlong JIN
- Publication Type:Journal Article
- Keywords:
Polycyclic aromatic hydrocarbons;
Genotoxicity;
DNA damage;
Chromosome damage;
Genetic susceptibility
- From:
Journal of Environment and Health
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Polycyclic aromatic hydrocarbons(PAHs) is a class of organic pollutants widely distributed in various environmental medium,and human exposure can occur by many routes (inhalation,ingestion,and skin contact),regardless of the source. PAHs can seriously impact human health and environment due to their high toxicity,stability. Studies on the toxicity of PAHs have involved in many fields,such as genotoxicity,hepatotoxicity,developmental toxicity,carcinogenesis and so on. The development of studies on genotoxicity of PAHs was reviewed in this paper,including DNA damage,chromosome damage and genetic susceptibility.