Expression of bone marrow-derived mesenchymal stem cells in spinal cord injury
- VernacularTitle:骨髓间充质干细胞修复脊髓损伤的临床研究现状
- Author:
Dexuan GAO
;
Quanzhang JIA
- Publication Type:Journal Article
- Keywords:
bone marrow-derived mesenchymal stem cells;
spinal cord injury;
clinical
- From:
Orthopedic Journal of China
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord injury is the main reason for paraplegia and one of the highest diseases causing human disability.Recent animals researches shows BMSCs has a good prospect in curing SCI,and these researches attracted doctors' attention from home and abroad,and they had achieved a certain effect,but long-term effects needs follow-up observation.In clinical the best time for transplanting BMSCs is about 9 days after SCI.Common methods:(1)Cell suspension injecting damaged parts directly.(2)Lumbar puncture cell suspension input.(3)Intravenous cell suspension input.(4)After the induced differentiation cell suspension.But with the development of basic research and clinical trial results,BMSCs could play an irreplaceable role in the treatment of spinal cord injury.