Immunohisochemical differential diagnosis of mesenteric fibromatosis, solitary fibrous tumors and gastrointestinal stromal tumors
- VernacularTitle:肠系膜纤维瘤、孤立性纤维性肿瘤和胃肠道间质瘤的免疫组织化学观察
- Author:
Juanhong SHI
;
Yan WANG
;
Qingsi HE
- Publication Type:Journal Article
- Keywords:
Interstitialoma?Immunohistochemistry??-catenin?CD117?Dog-1?CD34
- From:
Chinese Journal of Current Advances in General Surgery
1998;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the immunohistochemical features and the differential diagnosis of mesenteric fibromatosis (MF), solitary fibrous tumors (SFT)and gastrointestinal stromal tumors (GIST). Methods: The expressions of CD117, CD34, ?-catenin, S-100, Desmin, Bcl-2 and Dog-1 of the three tumors were studied by immunohistochemistry method (S-P method). Results: By immunohistochemical staining detection, the expression of ?-catenin in six MF cases were positive, the positive expression rates of CD117 and Dog-1 in GIST cases were 85% and 92% respectively, and the positive expression rates of CD34 and Bcl-2 in SFT were 71% . Conclusion: MF, SFT and GIST can be identified by the combining applying of CD117,CD34 and ?-catenin through the immunohistochemistry method.
