Storage & Distribution of No. Ⅱ Fluorocarbon Blood Substitute in Rats after Its Intravenous Administration
- VernacularTitle:Ⅱ号氟碳代血液静脉注入大鼠后的贮留和分布
- Author:
Rongde CHEN
- Publication Type:Journal Article
- From:Journal of Third Military Medical University
1984;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
No. II fluorocarbon blood substitute, also known as the PFC compound was injected intravenously into rats. Then the content of this compound in different tissues and oigans was determined at various intervals after the administration. It was found that the great majority of this compound was stored in the liver and spleen after its intravenous administration while only a small part was stored in the lungs and kidneys. As time went by, the amount stored in the tissues and organs would decrease. 90% of the PFC compound injected was eliminated out of the body in the eighth week after injection.When the gas chromatogram of PFC compound was compared with the standard one.no new peak on the spectrum was discovered. This fact indicates clearly that PFC compound is relatively inert, no changes of this compound occur in the body and it does not participate in the body metabolism.
