Experimental study of calcium phosphate cement and combined morselized bone in vitro
- VernacularTitle:磷酸钙骨水泥复合微小颗粒骨的体外实验研究
- Author:
Jianping LIANG
;
Xingyan LIU
;
Baofeng GE
- Publication Type:Journal Article
- Keywords:
calcium phosphate cement;
micromorselized bone;
mesenchymal stem cells;
tissue engineering
- From:
Orthopedic Journal of China
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To study the combination of calcium phosphate cement(CPC) and morselized bone and their optimum mixing ratio. [Methods]Bilateral nemora of macro-ears rabbits were made into morselized bone.There were two groups:experimental group and control group.In the experimental group,the ratios of morselized bone to CPC were 1 to 1,1 to 2,1 to 3,1 to 4 and 1 to 5.In the control group CPC was used after it was solidified.The maximum compression strength and solidified time of the materials in experimental and control groups were tested.The cell multiplication was evaluated by MTT after mesenchymal stem cells were cultivated.[Results]The cell multiplication in materials mixed with ratios of 1 to 2 and 1 to 3 was better than those in the materials mixed with the other ratios by MTT.It indicated that there was a significant difference(P
