Effects of Smoking on Arsenic Metabolism, Methylation:a Meta-analysis
- VernacularTitle:吸烟对人类砷代谢和甲基化影响的Meta分析
- Author:
Bo ZHU
;
Quanmei ZHENG
;
Yuanyuan XU
- Publication Type:Journal Article
- Keywords:
Arsenic;
Arsenicosis;
Smoking;
Meta-analysis
- From:
Journal of Environment and Health
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether smoking affects metabolism and methylation of arsenic. Methods Six papers about the relation between smoking and arsenic metabolism, methylation were collected until December,2008, and the data were quantitatively analyzed with random and fixed effect models. Results In the group of smoking, the summary weighted mean difference of percent of inorganic in urinary was 0.59 (95% CI:-0.01-1.18). The summary weighted mean difference of percent of MMA in urinary was 2.44 (95%CI:1.95-2.94). The summary weighted mean difference of percent of DMA in urinary was -3.04 (95%CI:-4.01- -2.07). Current evidence suggested that percent of MMA was higher, percent of DMA was lower in smoking or ever smoking group compared with nonsmoking group. Conclusion Smoking may be considered a risk factor for metabolism and methylation of arsenic on human.
