A Case of Kaposi's Sarcoma Occurring in Membranous Glomerulonephritis.
- Author:
Yoo Seok JEONG
1
;
Hyung Yoon PARK
;
Tae Ho PARK
;
Jae Hak YOO
;
Kea Jung KIM
Author Information
1. Department of Dermatology, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Kaposi's sarcoma;
Membranous glomerulonephritis
- MeSH:
Autoimmune Diseases;
Cryotherapy;
Dermis;
Drug Therapy;
Erythrocytes;
Foot;
Glomerulonephritis, Membranous*;
Hand;
Humans;
Immunocompromised Host;
Middle Aged;
Prednisolone;
Sarcoma, Kaposi*;
Skin
- From:Korean Journal of Dermatology
2003;41(1):135-137
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kaposi's sarcoma is a neoplasm of multifocal origin which manifests primarily as vascular nodules in the skin and other organs. Kaposi's sarcoma in iatrogenically immunocompromised patients is the result of immunosuppressive therapy in organ-transplant recipients, autoimmune disease patients and cytotoxic chemotherapy in cancer patients. We report a case of Kaposi's sarcoma in a 50-year-old man who developed well-defined purple-colored papules and plaques on both hands and feet after prednisolone treatment for underlying membranous glomerulonephritis. The histologic finding showed abnormally proliferated and dilated vessels, vascular slits, spindle-shaped cells and extravasated erythrocytes in the dermis. He was treated with cryotherapy, and the dosage of prednisolone was reduced. Improvement was seen in 6 weeks