Study the method of preparation and effect on isolated heart of rabbit and acute toxicity of Monkshood extract of Spa (Lao Cai province)
- Author:
Nguyen Trong Thong
- Publication Type:Journal Article
- Keywords:
monkshood extract
- MeSH:
Animal Experimentation;
Rabbits;
Heart;
Aconitum
- From:Pharmaceutical Journal
2005;0(8):12-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Method of proceping and preparation of Aconitum carmichacli. Its effect on mouse’s isolated heart and acute toxicity extract. Radix Aconitum carmichacli colected in Sapa was processed by traditional method (Hai Thuong Lan Ong method and liquid extract method). Total alcoloid content and aconitive content were reduced. The product processed by various methods give different activities of cardiotonic. Concerning the acute toxicity, no mouse died with oral maximal dose of 327,27g of radix Aconitum per kilograme body weight
