Study on Apoptosis Induced by Disodium Cantharidinate and Vitamin B6 Injection in Hepatocellular Carcinoma Cell Line HepG2
- VernacularTitle:斑蝥酸钠维生素B6诱导肝癌细胞HepG2凋亡的实验研究
- Author:
Hangyu ZHAO
;
Jian LIANG
- Publication Type:Journal Article
- Keywords:
Cantharidin;
Disodium Cantharidinate;
Vitamin B6;
Hepatocellular carcinoma;
Apoptosis
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the growth inhibision effect of disodium cantharidinate and Vitamin B6 injection on hepatocellular carcinoma cell line HepG2.Methods Different concentrations of disodium cantharidinate and Vitamin B6 injection were applied on the hepatocellular carcinoma cell line HepG2.The inhibition rate of HepG2 growth was measured by MTT assay.The apoptotic rate was detected with flow cytometry,and the morphology of apoptosis was observed by fluorescence microscope.Results The growth of HepG2 cells was significantly inhibited as well as the apoptosis of HepG2 cells was significantly encouraged by disodium cantharidinate and Vitamin B6 injection(P
