Expressions and Clinical Significance of MMP-2 and VEGF-C in Papillary Thyroid Carcinoma
- VernacularTitle:MMP-2和VEGF-C在甲状腺乳头状癌中的表达及临床意义
- Author:
Ligang WU
;
Qilun LIU
;
Zhiqiang HU
- Publication Type:Journal Article
- Keywords:
Papillary thyroid carcinoma;
Immunohistochemistry;
Matrix metalloproteinases-2;
Vascular endothelial growth factor-C
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions and clinical significance of matrix metalloproteinases-2(MMP-2) and vascular endothelial growth factor-C(VEGF-C) in patients with papillary thyroid carcinoma(PTC).Methods SP immunohistochemical technique was used to detect the expressions of MMP-2 and VEGF-C in 78 cases of PTC and 18 cases of thyroid benign tumors.Results The positive expression rates of MMP-2 and VEGF-C in PTC(80.77%,75.64%) were significantly higher than those of the thyroid benign tumor(11.11%,22.22%),P
