Effects of pyrroloquinoline quinone on proliferation and expression of NF-?B in cultured Schwann cells
- VernacularTitle:吡咯喹啉醌对雪旺细胞增殖及NF-?B表达的影响
- Author:
Bin HE
;
Shiqing LIU
;
Haohuan LI
- Publication Type:Journal Article
- Keywords:
pyrroloquinoline quinone;
Schwann cell;
proliferation;
NF-?B
- From:
Orthopedic Journal of China
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the effects of pyrroloquinoline quinine(PQQ)on proliferation and expression of NF-?B of Schwann cells.[Methods]Schwann cells were cultured from sciatic nerves of SD rats in vitro.The Schwann cells were identified and purified by immunofluorescence of S-100 and Ara-C.Experimental group with was 100 nmol/L of PQQ and control group were set up.The expression of NF-?B in Schwann cells was determined by RT-PCR and Western blotting.[Results]The expression of NF-?B were up-ragulated by PQQ in cultured Schwann cells(P
