Molecular basis of gastric cancer targeted therapy
- VernacularTitle:胃癌靶向治疗的分子基础
- Author:
Kaichun WU
;
Bei CHEN
- Publication Type:Journal Article
- Keywords:
gastric cancer;
targeted therapy;
immunotherapy
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is the second leading cause of cancer mortality worldwide,and in Asian countries like Japan,Korea and China,it remains the top killing cancer.As most cases of gastric cancer are in the advanced stage of the disease when they are first diagnosed,patients receiving conventional therapies including surgery,chemotherapy and radiotherapy have poor prognosis.An emerging modality called tumor molecular targeted therapy provides promise and insight to combat this malignancy.This article discusses the molecular basis of gastric cancer targeted therapy from the perspectives of screening and application of target molecules,modulation of tumor microenvironment and antitumor immunotherapy.
