Relationship between the expression of PTEN mRNA and protein in human brain glioma
- VernacularTitle:人脑胶质瘤PTEN基因mRNA和蛋白的表达及其相关性分析
- Author:
Xijun MENG
;
Yong LIU
;
Maode WANG
;
Wanfu XIE
- Publication Type:Journal Article
- Keywords:
glioma;
PTEN;
reverse transcription polymerase chain reaction(RT-PCR);
immunohistochemistry
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of the differential expression of PTEN in glioma tissue.Methods The mRNA and protein expressions of PTEN were assayed by reverse transcription polymerase chain reaction(RT-PCR) and immunohistochemistry in 75 human brain glioma cases.Results The positive expression rate mRNA of PTEN differed significantly between brain glioma tissue and normal brain tissue(?2=22.66,P
