Mechanism Study Progress of Gastrointestinal Bypass Operation on Treatment of Type 2 Diabetes Mellitus
- VernacularTitle:胃肠转流手术治疗2型糖尿病作用机理的研究进展
- Author:
Yamin ZHENG
;
Fei LI
;
Di ZHANG
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Gastric bypass operation
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of gastric bypass operation on treatment of type 2 diabetes mellitus,recognize the etiology and pathogenesy of the disease and frame therapy strategy for type 2 diabetes mellitus.Methods The literatures about gastric bypass operation on treatment of type 2 diabetes mellitus,including clinical cases reports and evidence-based studies were reviewed.Results Gastrointestinal bypass operation was regarded as an effective treatment for type 2 diabetes mellitus.There were three hypotheses of therapy mechanism: early delivery of nutrients to the distal intestine,exclusion of the proximal intestine and incretin/anti-incretin.Conclusion Gastrointestinal bypass operation is now considering as an effective treatment,there is still a lack of basic experimental studies to clarify the mechanism.
