A new NK cell subset with antigen presentation function:IKDC cells
- VernacularTitle:具抗原呈递功能的NK细胞新亚群:IKDC细胞
- Author:
Hui PENG
;
Zhigang TIAN
- Publication Type:Journal Article
- Keywords:
NK cells;
DC;
IKDC;
Innate immunity;
Adaptive immunity
- From:
Chinese Journal of Immunology
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
A new NK cell subset with antigen presentation function was recently found and called as interferon-producing killer dendritic cells (IKDC cells).These cells co-express surface markers of NK cells and DCs;functionally,they can secrete interferons,kill target cells and have antigen-presenting ability.IKDCs extensively exist in almost all lymphoid tissue or organs with similar phenotype,but recent studies indicated that IKDCs were developmently not from DC cells but from NK cells,the conclusion of which is still in its early stage.The discovery of IKDC will be help to understand the link between innate and adaptive immunity.
