The important factors influencing the functions of periodontal ligament stem cells
- VernacularTitle:影响牙周膜干细胞功能的重要因素
- Author:
Tang LIANG
;
Jin YAN
- Publication Type:Journal Article
- Keywords:
Periodontium;
Periodontal ligament stem cells;
Microenvironment;
Cell differentiation
- From:
Journal of Practical Stomatology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Periodontal ligament stem cells(PDLSCs) are not only the crucial type of cells in maintaining dynamic homeostasis and wound repair of periodontal tissues but also the basis for novel therapeutic strategy for periodontal regeneration.Although possessing the excellent proliferation and differentiation ability,PDLSCs behave differently under various conditions representative of several influential factors.Understanding of these influential factors will help us to exploit more about PDLSCs,and more importantly,lead a new modality in treating periodontal diseases based on stem cells.Here we review multiple important factors affecting function of PDLSCs and propose its use in future regenerative therapy of periodontal defects.