Expression and Clinical Significance of Connective Tissue Growth Factor in Colorectal Cancer
- VernacularTitle:结缔组织生长因子在结直肠癌中的表达及临床意义
- Author:
Picheng SI
;
Jianguo XU
;
Huimin HUANG
;
Litao LI
- Publication Type:Journal Article
- Keywords:
Connective tissue growth factor;
Colorectal cancer;
Gene expression;
Immunohistochemical method
- From:
Chinese Journal of Bases and Clinics in General Surgery
2008;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and clinical significance of connective tissue growth factor(CTGF) in colorectal cancer.Methods The expressions of CTGF in 62 patients' colorectal cancer tissues and their corresponding adjacent tissues were detected by SP immunohistochemical method.The results were statistically analyzed.Results The positive rates of CTGF in colorectal cancer and adjacent tissues were 61.3% and 19.4% respectively,and the difference between them was significant(P0.05).Conclusion CTGF may play an important role in the occurrence of colorectal cancer,which contributes a lot to guide clinical treatment and prognosis.
