Changes of Protein Metabolism in Rat Liver after Scaldingand Effects of Insulin
- VernacularTitle:烫伤大鼠肝脏蛋白质合成变化及胰岛素的影响
- Author:
Taosheng HUANG
;
Yanling DONG
- Publication Type:Journal Article
- Keywords:
Scalding;
Protein metabolism;
Liver;
Insulin
- From:Journal of Third Military Medical University
1986;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Full thickness scalding of 37% TBSA was inflicted io rats. Three days later, the liver of the animals was isolated and the changes of the protein metabolism in the liver and the effects of insulin on the changes were evaluated.It was found that the protein and DMA levels of the liver showed no obvious changes after scalding, but the RNA content increased by 24% and the rate of leucine incorporation by 31%. After the addition of insulin, the leucine content increased by 23.% and 25.8% in the controls and the injured animals respectively. The results indicate that the rate of protein synthesis in the liver of the scalded animals increases, which is likely to be related to the increase of RNA content, and the liver protein synthesis remains to be sensitive to insulin.
