Mobile Vehicle Exhaust Exposure and Impacts of Cardiovascular System in Middle and Old Aged People:a panel Study in a Community of Guangzhou
- VernacularTitle:机动车尾气暴露对广州某社区中老年人心血管系统影响的panel研究
- Author:
Boning CHEN
;
Hong SONG
;
Ganjing WEN
- Publication Type:Journal Article
- Keywords:
Air pollution;
Vehicle exhaust pollution;
Middle and old aged people;
Cardiovascular system
- From:
Journal of Environment and Health
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explored the effects of vehicle exhaust on the cardiovascular system in a panel of 32 middle and old aged people,to discover the sensitive effect indicators of vehicle exhaust. Methods Thirty-two middle and old aged people living near a main road were followed-up,The health-related indicators and individual time-weighted outdoor exposure concentration of air pollutants were determined;The mixed model was used to evaluate association between vehicle exhaust and health indicators of cardiovascular system. Results In single-pollutant models,TNF-? was positively associated with PM10,SO2,NO2 and FVC,IL-6 was negative. The indicators of heart rate variability(HRV) in SDNN(?:-0.57,SE:0.18) ,SDNN index(?:-0.74,SE:0.20) had a strong association with PM10,and NO2 related indicators was SDNN index(?:-0.66,SE:0.17) . In the multi-pollutant model,after adjusting the effect of other pollutants,IL-6 had a positive correlation with PM10;And TNF-? was positively correlated to NO2,SO2;FVC had a negative correlation with PM10. Conclusion The air pollutants of this location show a vehicle exhausts characteristic,and the pollution is serious;TNF-?,IL-6,FVC,SDNN,SDNN index are closely related to exposure of the vehicle exhaust,and can be used to evaluate the effects of vehicle exhaust pollution on the cardiovascular system of the elderly.