DYNAMIC CHANGES OF PIAL-MICROCIRCULATION IN RATS DURING HEMORRHAGIC SHOCK
- VernacularTitle:大鼠失血性休克时软脑膜微循环的动态变化
- Author:
Bo REN
- Publication Type:Journal Article
- Keywords:
shock, hemorrhagic;
pial-microcirculation
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
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Abstract:
The influence of shock in varied degrees on pial-microcirculation in rats and the dynamic change of pial-microcirculation in hypotension were observed. It was shown that severe disturbance occurred in pial-microcirculation when blood ressure was lowered to 3.20 kPa.In early stage after severe bleeding the main manifestation of pial-microcirculatory disturbance was hyperemia, i. e., dilatation of arteriole or segmental dilatation-contraction of arteriole, hyperemia of capillary net, increased number of opened capillaries and appearance of 0-I degree of blood flow status (according to the classification of Tia Niu).Ninety minutes after bleeding arterioles and venules became gradually constricted,red blood cells aggregation was increased, ischemia of pial-microcirculation became more severe and blood flow status changed from 1st to 2nd, even 3rd degree.The results demonstrate that autoregulation of cerebral microcirculation is much stronger than that of other organs. Microcirculatory disturbance does not appear until blood pressure drops to the degree beyond the ability of autoregulation.
