Autoantibodies:the early diagnostic biomarkers for tumors
- VernacularTitle:自身抗体——肿瘤新的早期诊断标志物
- Author:
Guancheng LI
;
Yongqing TONG
- Publication Type:Journal Article
- Keywords:
autoantibody;
tumor biomarker;
early diagnosis;
tumor antigen
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1982;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Tumor markers refer to the specific substances that exist in tumor cells themselves or are secreted by tumor cells. They can reflect the existence and growth of the tumor. The serum tumor biomarkers have been widely applied in tumor detection,but the detection of these markers is based on the tumor antigens,and thus has many inadequacies in tumor screening and diagnosis. In this paper,we reviewed autoantibodies as tumor biomarkers against self-antigens in vivo. This method is to examine the tumor autoantibodies by using the tumor antigens,and its specificity and sensitivity are superior to the traditional examination methods. Using autoantibodies to detect tumors would provide a new method for tumor screening and diagnosis.