Effect of reconstituted bone xenografts on tendon-to-bone healing after anterior cruciate ligament reconstruction
- VernacularTitle:应用重组合异种骨促进前交叉韧带重建术后腱-骨愈合的研究
- Author:
Weimin PAN
;
Yunyu HU
;
Yiyong WEI
- Publication Type:Journal Article
- Keywords:
reconstituted bone xenografts;
reconstruction of anterior cruciate ligament;
tendon grafts;
bone tunnel;
tendon to bone healing
- From:
Orthopedic Journal of China
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the effect of reconstituted bone xenografts(RBX) on tendon-to-bone healing by means of imaging,histological and biomechanical studies.[Method]Anterior cruciate ligament(ACL) reconstruction was performed bilaterally in 25 skeletally mature rabbits using long digital extensor tendon grafts.RBX were implanted into the treated knee of each rabbit,with the contralateral knees as controls.Every three rabbits were killed at 2,6 and 12 weeks postoperatively for routine histological studies.The samples were processed through Micro CT and subsequent HE and toludine blue staining.The remaining 16 rabbits were sacrificed at 6 and 12 weeks.Their femur-tendon graft-tibia complexes were harvested for subsequent mechanical testing.[Result]At 6 and 12 weeks after operation,the values of BMD in the RBX group were higher than those in the control group(P