Preparation of rh-BMP-2 loaded chitosan microsphere and its properties in vitro
- VernacularTitle:rh-BMP-2壳聚糖微球的制备及体外检测
- Author:
Xin HUANG
;
Guolin MENG
;
Jian LIU
- Publication Type:Journal Article
- Keywords:
rhBMP-2;
chitosan;
microsphere;
bone formation;
genipin
- From:
Orthopedic Journal of China
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
85%).From the in vitro release experiment,the rhBMP-2 was controlled to release from the chitosan microsphere over 30 days.[Conclusion]The rhBMP-2 loaded chitosan microsphere prepared by emulsion cross-linking method shows a good controlled release property.Such a novel type of controlled release system has the potential of being applied for controlled cytokine delivery and the bone tissue engineering.