Correlation of somatostatin and vascular endothelial growth factor receptor KDR expression with angiogenesis in pancreatic carcinoma and its clinical significance
- VernacularTitle:生长抑素和KDR表达与胰腺癌血管形成关系及临床意义
- Author:
Peng LI
;
Qingdong ZENG
;
Bin WANG
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms?Vascular endothelial growth factor receptor-2?Somatostatin?Microvessel denstity
- From:
Chinese Journal of Current Advances in General Surgery
2009;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the correlation between the expression of vascular endothelial growth factor receptor KDR ,somatostatin (SS) and angiogenesis in pancreatic carcinoma and their association with the clinicopathologic characterizations. Methods:Immunohistochemical SP technique was used to detect the expression of KDR and SS. Microvessel density was determined by immunostaining for factor CD34 related antigen. Results:MVD was higher in KDR high and middle expression cases than that in low expression cases(P