Effects of short-term insulin pump treatment on pancreatic ?-cells in newly diagnosed type 2 diabetes mellitus
- VernacularTitle:短期胰岛素泵治疗对初诊2型糖尿病患者胰岛?细胞功能的影响
- Author:
Fuzhen LIU
;
Wenpu CHEN
;
Yu CHEN
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
insulin pump;
blood glucose;
insulin;
?-cells
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of insulin pump on pancreatic ?-cells in type 2 diabetes mellitus accompanied with hyperglycaemia.Methods We treated 46 cases of newly diagnosed type 2 diabetes mellitus with fasting blood glucose≥10.0 mmol/L by insulin pump for 2 weeks.Their blood sugar and insulin were determined before and after treatment by oral glucose tolerance test and insulin releasing test.We then calculated the function index,morning secretion of pancreatic ?-cells and insulin resistance index.The patients were followed up for 6 months and the blood glucose was monitored.Results After treatment,insulin,function index and the morning secretion were increased significantly,while the blood sugar and resistance index were decreased.In all the patients,16 could maintain ideal blood glucose only by alimentary control and exercise.Conclusion With the insulin pump in a short term,patients with type 2 diabetes mellitus can rapidly control blood glucose,obviously improve pancreatic ?-cells,and reduce insulin resistance.
