Increased expression of Zbtb7 mRNA in leukemia cell lines induced by PMA
- VernacularTitle:Zbtb7基因mRNA在佛波酯诱导的白血病细胞分化中表达上调
- Author:
Lifang WANG
;
Zhibo HAN
;
Ying HUANG
;
Peng DU
;
Aihua SUN
- Publication Type:Journal Article
- Keywords:
leukemia;
Zbtb7 gene;
mRNA;
expression
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the expression of Zbtb7 gene in Phorbol esters(PMA) induced differentiation of leukemia cell lines.Methods 50 nmol/L PMA was used to induce the differentiation of U937 and K562 cell lines.The expression of Zbtb7 was detected by real-time PCR in the cells after induction on day 0,1,3 and 5,respectively. Results The expression of Zbtb7 in leukemia cell lines was markedly enhanced after treated by PMA(P
