PREPARATION OF RATE-CONTROLLING MEMBRANE OF TRANSDERMAL SODIUM NITROPRUSSIDE DELIVERY SYSTEM
- VernacularTitle:硝普钠透皮递药系统控释膜的制备
- Author:
Bingqing JI
- Publication Type:Journal Article
- Keywords:
sodium nitroprusside: polyvinyl alcohol;
rate-controlling membrane
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The permeation properties of several synthetic polymeric films for sodium nitroprusside (SNP) were studied with respect to their potential application for the control of drug release.One of the films, the heat-treated polyvinyl alcohol(PVA) membrane which appeared to be the most promising, was further investigated to determine the factors influencing its permeability.It was found that the permeability of SNP through the PVA membrane could be controlled by appropriate adjustment of temperature and time of the heat-treatment.
