Tendon tissue engineering and gene transfer
- VernacularTitle:肌腱组织工程和基因转染
- Author:
Deqing HUANG
;
Yanru FENG
- Publication Type:Journal Article
- Keywords:
tendon injury;
repair and regeneration;
mescenchymal stem cell;
growth/differentiation;
tissue engineering;
gene therapy
- From:
Orthopedic Journal of China
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Currently,bone marrow derived mescenchymal stem cells(MSCs) are the best available cell population for tendon tissue engineering.Recent adipose-derived MSCs show characteristics of multipotentital and may be used as functional cells for tendon tissue engineering.Nanofiber scaffolds can mimic the structure and function of extracellular matrix,and have advantages for tendon tissue engineering.A variety of gene transfer techniques can be used to maintain local concentrations of growth factor at tendon repair site.Although tremendous progress has been achieved in the field of tendon tissue engineering,many challenges remain and much work still needs to be done.
