Water channel protein AQP3 expression in activated human T lymphocytes
- VernacularTitle:激活的人外周T淋巴细胞表达水通道蛋白AQP3
- Author:
Xiufang KAN
;
Lifeng LIU
;
Jianguo ZHU
;
Dan ZHAO
- Publication Type:Journal Article
- Keywords:
Aquaporin;
AQP3;
Lymphocyte;
Active immunocyte
- From:
Chinese Journal of Immunology
1985;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression and physiological significance of water channel proteins in human T lymphocytes.Methods:AQP0-9 mRNA and protein in inactivated and activated human T lymphocytes were analyzed using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis and Western blot.Results:No AQP was expressed in inactivated lymphocytes.However,AQP3 mRNA and protein were expressed in PHA activated T lymphocytes.Conclusion:Water and glycerol transport mediated by AQP3 may be important in T lymphocyte activation.
