Advance for Development of In Vitro Methods of Skin Sensitization Test
- VernacularTitle:皮肤变态反应体外替代方法研究进展
- Author:
Shunjing DU
;
Jun FANG
;
Yinlong JIN
- Publication Type:Journal Article
- Keywords:
Skin sensitization test;
Alternatives;
In vitro test;
Allergen
- From:
Journal of Environment and Health
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Due to a greater emphasis placed on non-animal test and our deeper understanding of allergic contact dermatitis,many researchers have tried several approaches in developing an in vitro skin sensitization test.The development of in vitro methods for predicting contact sensitization potential was reviewed in this paper,including cell-based methods,human skin equivalent/reconstituted epidermis cultures,peptide/protein reactivity,and quantitative structure-activity relationship.
