Expression and clinical significance of Kiss-1 and KAI-1 in colorectal cancer
- VernacularTitle:Kiss-1和KAI-1在大肠癌组织中的表达及临床意义
- Author:
Wenchang SANG
;
Qingsi HE
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms?Kiss- 1?KAI- 1?Tumor suppression
- From:
Chinese Journal of Current Advances in General Surgery
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression and clinical significance of metastasis suppressor gene Kiss-1 and KAI-1 in colorectal cancer. Methods: In situ hybridization was used to detect and analyze the gene expression of Kiss-1 and KAI-1 in 61 cases of colorectal cancer and 20 cases of normal para cancer tissue. Results: In situ hybridization revealed that the positive expression rates of Kiss-1 and KAI-1 in colorectal cancer were significantly lower than those in normal para cancer tissue (P