Correlation of serum TSH and thyroid autoantibodies with cytopathologic changes of thyroid in autoimmune thyroiditis
- VernacularTitle:自身免疫性甲状腺炎患者血清TSH、甲状腺自身抗体与甲状腺细胞病理学改变的相关性
- Author:
Yuan ZHAO
;
Bingyin SHI
;
Bangqiang XU
;
Li XU
- Publication Type:Journal Article
- Keywords:
autoimmune thyroiditis;
cytopathology;
TSH;
thyroid autoantibody
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
1981;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship of serum levels of TSH,thyroid peroxidase antibody(TPOAb) and thyroglobulin antibody(TGAb) with cytopathologic changes of thyroid fine needle aspiration(FNAB) in autoimmune thyroiditis(AIT).Methods Totally 82 cases of cytologically confirmed AIT including 75 females and 7 males were collected.Levels of TSH,TPOAb and TGAb were tested.After execution of FNAB,features of the cytopathology were observed.Results ① The percentage of positive TPOAb and TGAb were 91.4% and 74.4%,respectively in all the AIT patients.47.6% of the patients had TSH levels within normal range(0.3～5 mu/L).② All of the slides had different grades of lymphocytic infiltration.49.3% had germinal center,32.8% had Askanazy cells,26.9% had plasma cells,22.4% had colloid,and 9% had multinuclear giant cells.③ Lymphocytic infiltration was divided into four degrees.The levels of TSH and TPOAb increased significantly in the extremely heavy lymphocytic infiltration grade than in the others(P
