Infective stages and clearaim should be held on HVB control
- VernacularTitle:要明确乙型肝炎病毒感染控制的阶段和目标
- Author:
Jun CHENG
- Publication Type:Journal Article
- Keywords:
hepatitis B,chronic;
hepatitis B vaccines;
antiviral agents;
liver cirrhosis
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Chronic hepatitis B virus(HBV) infection is not only a medical problem,but a social and psychiatry problem.The consequence is quiet different for the infected person at different time of life.The final control of HBV infection resulted from steps on antiviral therapy.HB vaccination plays an important role for protection of uninfected persons and changes prevalence of HBV infection in high epidemic area.Not all the HBV infected patients need to be treated immediately,but only for those have active inflammation and fibrosis.Interferon alpha and nucleos(t)ide analogues including lamivudine,adefovir,entecavir and LdT are the first line choice for the treatment of the patients with chronic HBV infection.The final goal of antiviral therapy should be clinical resolution,but not viral,immunological,and histological improvements.The management of CHB is still a problem although many clinical achievements in recent years.