The value of bile CEA assay in detection of liver metastasis in patients with colorectal cancer
- VernacularTitle:胆汁中CEA浓度测定在大肠癌肝转移诊断中的意义
- Author:
Kai ZHU
;
Guangfa ZHAO
;
Yingjian ZHANG
- Publication Type:Journal Article
- Keywords:
carcinoembryonic antigen;
colorectal cancer;
neoplasm metastasis;
liver;
bile
- From:
China Oncology
1998;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Background and purpose:Carcinoembryonic antigen(CEA) is mainly used in post-surveillance of colorectal cancer(CRC). Recently, bile CEA assay was reported to be of value in the diagnosis of OHM(occult hepatic metastasis) in CRC. We measured CEA levels in both peripheral vein and bile from patients with CRC to evaluate the change of bile CEA levels in patients with CRC and its relation to liver metastasis (LM). Methods:Three groups were enrolled in our study. Primary CRC Group: 27 patients with CRC but without LM; LM Group: 14 patients with LM from CRC; Control Group: 20 patients with benign biliary diseases (cholelithiasis or cholecystitis). Both serum and bile were collected to measure CEA levels in all groups but only bile CEA was measured in control group. Results:Bile CEA level in control group, primary CRC group and LM group were 1.73 ng/ml,13.7 ng/ml and314.27 ng/ml respectively, (P
