Tissue engineering cbondrogenesis :an experiment study of bone mesenchymal stem cells
- VernacularTitle:骨髓干细胞体外组织工程软骨形成的实验研究
- Author:
Shifeng SONG
;
Haitao XIAO
;
Wei WU
- Publication Type:Journal Article
- Keywords:
bone mesenchymal stem cells;
cellular carrier;
chondrogenesis;
tissue engineering
- From:
Orthopedic Journal of China
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To investigate the chondrogenic ability and feasibility of bone mesenchymal stem cells(BMSCs) in three kinds of cellular carrier.[Method]BMSCs were separated and cultured into the third generation,which were cultivated in three knids of carriers by multi-point injection into and dropping on the surface of carriers(fibrin collagen sponge,group A;fibrin collagen sponge and FGF,group B and gelatin sponge,group C).All samples were analyzed after four weeks.[Result]There were a few chondrogenic cells in group A,much more chondrogenic cells in group B,and no cells in group C.According to analysis with SPSS 10.0 software,There were more cartilage cells(92.75?10.57) in group B than in group A(36.45?8.34).It was statistical different(P
